By Roger Narayan, Paolo Colombo, Dileep Singh, Jonathan Salem
Increase your knowing within the most beneficial features of advances in bioceramics and porous ceramics. This selection of logically equipped and punctiliously chosen articles include the court cases of the “Porous Ceramics: Novel advancements and functions” and “Next iteration Bioceramics” symposia, that have been hung on January 27-February 1, 2008.
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Extra resources for Advances in Bioceramics and Porous Ceramics II
43 Novel Bioceramics for Bone Implants Figure 4: SEM micrographs showing the morphology of a spherical cell attached to several eCA-nHA fibers (day 3 of seeding) at 20kx and different voltages: (a) 20 kV; circles highlight the hydroxyapatite aggregates at the areas where the cell contacts the fibers (b) 5 kV; image details how the cell attaches to the fibers. Figure 5: SEM micrographs showing the morphology of a flat and spread out cell attached to eCAnHA fibers on day 3. (a) 5kx and 20 kV displaying morphology of elongated cells (b) at lOkx and 5 kV; higher magnification of the flattened cell elaborating a large number of pseudopodia overlying the fine eCA fibers.
Less spherical) morphology. The flatter cells are seen to spread out along the mesh-like fiber network, and several fibers are visualized interlocking individual fibers on the cell surface (Figures 5). Again, the nHA aggregates are well dispersed throughout the eCA fibers, but the cells do not appear to incorporate these aggregates (Figure 5). DISCUSSION This study explores the feasibility of using eCA and eCA-nHA composite hybrid mats as scaffolds for bone tissue engineering applications. The MTS viability assay demonstrated that the cells exposed to these scaffolds maintain the ability to proliferate for up to 3 days.
Products were milled in ethanol solvent for 10 h by ball mill, after which polyethylene glycol (PEG) was added to portions of the powder. Batches were sieved with 100 pm mesh and green compacts were formed through dry pressing at 220 MPa. HA samples were then sintered in air at 900°C for 2 h while limiting the heating rate to 2"Cimin. The structural and morphological evolution of HA particles has been recently detailed . The sintered HA was crushed to powder form in order to introduce HA into the CA solution.
Advances in Bioceramics and Porous Ceramics II by Roger Narayan, Paolo Colombo, Dileep Singh, Jonathan Salem